Formulation
Antioxidant Network Calculator
Antioxidants work in a cascade — Vit C recycles Vit E, ferulic stabilizes both, and chelators stop pro-oxidant metals. Build a blend that covers aqueous, lipid, and interface phases without pH conflicts.
L-Ascorbic Acid needs pH 2.5–3.5; SAP/MAP work at skin-neutral 5–7.
Antioxidant blend
Aqueous · pot 5
Lipid · pot 4
Interface · pot 4
Chelator · pot 5
Coverage
Coverage score
100 / 100
Phases covered
4 / 4
aqueous · lipid · interface · chelator
Radical types
5 / 5
broader = better
Aqueous
5
Lipid
4
Interface
4
Chelator
5
Radicals neutralized
Peroxyl (ROO•)Hydroxyl (•OH)Superoxide (O₂•⁻)Singlet oxygen (¹O₂)Pro-oxidant metals
Regeneration loops
- L-Ascorbic Acid (Vit C)→ recycles →Tocopherol (Vit E)
- Ferulic Acid→ recycles →Tocopherol (Vit E)
- Ferulic Acid→ recycles →L-Ascorbic Acid (Vit C)
Issues & guidance
- ✗ L-Ascorbic Acid (Vit C) requires pH 2.5–3.5 (formula is 5).
- ✗ Ferulic Acid requires pH 3–4 (formula is 5).
The C+E+Ferulic combination (Lin et al., 2005) is the gold-standard daytime antioxidant network for melanin-rich skin under UV stress.